diff --git a/include/boost/python/detail/config.hpp b/include/boost/python/detail/config.hpp
index 7997783c..7377fb2d 100644
--- a/include/boost/python/detail/config.hpp
+++ b/include/boost/python/detail/config.hpp
@@ -12,7 +12,7 @@
 #ifndef CONFIG_DWA052200_H_
 # define CONFIG_DWA052200_H_
 
-#if !(defined(_WIN32) && defined(__MWERKS__))
+#if defined(__ALPHA) && defined(__osf__) && defined(__DECCXX_VER)
 # include <pyconfig.h>
 #endif
 # include <boost/config.hpp>
diff --git a/include/boost/python/detail/wrap_python.hpp b/include/boost/python/detail/wrap_python.hpp
index 79998311..c94626f8 100644
--- a/include/boost/python/detail/wrap_python.hpp
+++ b/include/boost/python/detail/wrap_python.hpp
@@ -24,7 +24,7 @@
 // Python's LongObject.h helpfully #defines ULONGLONG_MAX for us,
 // which confuses Boost's config
 //
-#if !(defined(_WIN32) && defined(__MWERKS__))
+#if defined(__ALPHA) && defined(__osf__) && defined(__DECCXX_VER)
 # include <pyconfig.h>
 #endif
 #include <limits.h>
diff --git a/include/boost/python/has_back_reference.hpp b/include/boost/python/has_back_reference.hpp
index 8954dd91..63313e79 100644
--- a/include/boost/python/has_back_reference.hpp
+++ b/include/boost/python/has_back_reference.hpp
@@ -6,7 +6,7 @@
 #ifndef HAS_BACK_REFERENCE_DWA2002323_HPP
 # define HAS_BACK_REFERENCE_DWA2002323_HPP
 
-#if !(defined(_WIN32) && defined(__MWERKS__))
+#if defined(__ALPHA) && defined(__osf__) && defined(__DECCXX_VER)
 # include <pyconfig.h>
 #endif
 #include <boost/config.hpp>
diff --git a/include/boost/python/object_core.hpp b/include/boost/python/object_core.hpp
index 68b3e691..8b924622 100755
--- a/include/boost/python/object_core.hpp
+++ b/include/boost/python/object_core.hpp
@@ -6,7 +6,7 @@
 #ifndef OBJECT_CORE_DWA2002615_HPP
 # define OBJECT_CORE_DWA2002615_HPP
 
-#if !(defined(_WIN32) && defined(__MWERKS__))
+#if defined(__ALPHA) && defined(__osf__) && defined(__DECCXX_VER)
 # include <pyconfig.h>
 #endif
 # include <boost/type.hpp>
diff --git a/include/boost/python/ptr.hpp b/include/boost/python/ptr.hpp
index d80c55ac..4deac448 100644
--- a/include/boost/python/ptr.hpp
+++ b/include/boost/python/ptr.hpp
@@ -14,7 +14,7 @@
 #  pragma once
 # endif
 
-#if !(defined(_WIN32) && defined(__MWERKS__))
+#if defined(__ALPHA) && defined(__osf__) && defined(__DECCXX_VER)
 # include <pyconfig.h>
 #endif
 # include <boost/config.hpp>